Thermo Fisher Scientific DRD2 Monoclonal Antibody (629CT62.2.2)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:200-1:800

-

Product Specifications

Host/Isotype

Mouse / IgG2a

Class

Monoclonal

Type

Antibody

Clone

629CT62.2.2

Immunogen

KLH conjugated synthetic peptide between 307-336 amino acids from the C-terminal region of human DRD2 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:DRD2,uniProtId:P14416-1,ncbiNodeId:9606,antigenRange:307-336,antigenLength:443,antigenImageFileName:MA5-37607_DRD2_P14416-1_House_mouse.svg,antigenImageFileNamePDP:MA5-37607_DRD2_P14416-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

Conc. not determined

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

Target Information

The DRD2 Dopamine Receptor is involved in the neuromodulation of appetitive behaviors. DRD2 may be linked to alcoholism and other substance-use disorders. Mutations in DRD2 in mice lead to the suppression of reward behavior with morphine and to the reduction of spontaneous movements, a phenotype resembling Parkinsons disease. Three alternatively spliced isoforms have been identified. DRD2 has been reported to be expressed in various regions of the brain, as well as in aorta, artery, eye, and spinal cord. ESTs have been isolated from normal pituitary and in brain, colon, lung, pancreas, and skeletal muscle cancer libraries.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.