Thermo Fisher Scientific HSP27 (Heat Shock Protein 27) Monoclonal Antibody (G3.1)
HSP27 단백질을 인식하는 Thermo Fisher Scientific의 G3.1 단일클론 항체. Western blot, IHC, ICC, Flow cytometry 등 다양한 응용에 적합. Protein A/G 정제, 액상 형태, 200 µg/mL 농도. 인간 및 여러 종에 반응하며 연구용으로만 사용.
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Thermo Fisher Scientific HSP27 (Heat Shock Protein 27) Monoclonal Antibody (G3.1)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Chicken, Chimpanzee, Human, Mouse, Non-human primate, Sheep, Rat |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | G3.1 |
| Immunogen | Partially purified hsp27 (earlier called 24K) protein from breast cancer MCF-7 cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
In response to adverse changes in their environment, cells from many organisms increase the expression of a class of proteins referred to as heat shock or stress proteins.
HSPB1 (heat shock protein beta-1 or HSP27) is a small heat shock protein functioning as a molecular chaperone that maintains denatured proteins in a folding-competent state.
It plays a role in stress resistance and actin organization. Through its molecular chaperone activity, HSP27 regulates numerous biological processes including phosphorylation and axonal transport of neurofilament proteins.
Mutations in the gene can result in Charcot-Marie-Tooth disease 2F and Neuronopathy distal hereditary motor 2B.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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