Thermo Fisher Scientific ATP2C1 Polyclonal Antibody
ATP2C1 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, ICC/IF에 적합. 인간 ATP2C1 재조합 단백질을 면역원으로 사용하며, 토끼 IgG 형식의 비결합 액상 제품. Hailey-Hailey 질환 및 세포 내 Ca2+/Mn2+ 운반 연구에 활용 가능.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific ATP2C1 Polyclonal Antibody
Thermo Fisher Scientific ATP2C1 Polyclonal Antibody
Applications
- Immunocytochemistry (ICC/IF)
Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human ATP2C1 (amino acids 356–427) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2663112 |
Product Specific Information
- Immunogen sequence:
TKNEMTVTHIF TSDGLHAEVT GVGYNQFGEV IVDGDVVHGF YNPAVSRIVE AGCVCNDAVI RNNTLMGKPT E - Highest antigen sequence identity: mouse 99%, rat 99%
Target Information
ATP2C1, also known as secretory pathway Ca²⁺/Mn²⁺-ATPase (SPCA1), belongs to the family of P-type cation transport ATPases.
This magnesium-dependent enzyme catalyzes ATP hydrolysis coupled with calcium transport from the cytosol to the Golgi lumen.
Defects in ATP2C1 cause Hailey-Hailey disease, an autosomal dominant disorder characterized by persistent blisters and skin erosions.
Unlike the related ATP2C2 protein, ATP2C1 is ubiquitously expressed and shows a lower maximal turnover rate for Ca²⁺-ATPase reaction but a higher affinity for cytosolic Ca²⁺.
Recent studies suggest ATP2C1 regulates IGF1R processing in tumor progression of basal breast cancers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.