Thermo Fisher Scientific GEF-H1 Monoclonal Antibody (K.607.1)
GEF-H1 단백질을 인식하는 토끼 단클론 항체로, Western blot에 최적화되어 있습니다. 인간, 마우스, 랫트 등 다양한 종에 반응하며, Rho GTPase 관련 세포 신호 연구에 적합합니다. 액상 형태로 제공되며, -20°C에서 보관합니다.
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Applications
- Western Blot (WB): 1:1,000
- View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Hamster, Human, Mouse, Non-human primate, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | K.607.1 |
| Immunogen | Synthetic peptide corresponding to the sequence of human GEF-H1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 33 µg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | <0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_10985904 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
GEF-H1 activates Rho GTPases by promoting the exchange of GDP and GTP.
Rho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli acting through G protein coupled receptors.
GEF-H1 may be involved in epithelial barrier permeability, cell motility and polarization, dendritic spine morphology, antigen presentation, leukemic cell differentiation, cell cycle regulation, innate immune response, and cancer.
Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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