Thermo Fisher Scientific Histone H2A Recombinant Rabbit Monoclonal Antibody (15H4L7)

Applications

• Western Blot (WB)
  Tested Dilution: 0.1–2 µg/mL
  View 1 publication

Product Specifications

Product Specific Information

This antibody is predicted to react with mouse based on sequence homology.
Intact IgG appears on a non-reducing gel as ~150 kDa band and upon reduction generates a ~25 kDa light chain band and a ~50 kDa heavy chain.

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select optimal candidates for production.

Advantages of recombinant rabbit monoclonal antibodies:

• Better specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulations
• Broader immunoreactivity due to larger rabbit immune repertoire

Target Information

Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fibers in eukaryotes.
Two molecules of each core histone (H2A, H2B, H3, H4) form an octamer, around which approximately 146 bp of DNA is wrapped to form nucleosomes.
The linker histone H1 interacts with linker DNA between nucleosomes, aiding chromatin compaction into higher-order structures.
This gene is intronless, encodes a member of the histone H4 family, and its transcripts lack polyA tails, containing instead a palindromic termination element.
Located in the large histone gene cluster on chromosome 6.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지

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