
Thermo Fisher Scientific Histone H2A Recombinant Rabbit Monoclonal Antibody (15H4L7)
Recombinant rabbit monoclonal antibody targeting human Histone H2A (aa 2–19). Validated for Western blot in human, mouse, and non-human primate samples. Offers high specificity, lot-to-lot consistency, and animal-origin-free formulation. Suitable for r...
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Applications
- Western Blot (WB)
Tested Dilution: 0.1–2 µg/mL
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Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 15H4L7 |
| Immunogen | A peptide corresponding to amino acids 2–19 of human Histone 2A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at −20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2532288 |
Product Specific Information
This antibody is predicted to react with mouse based on sequence homology.
Intact IgG appears on a non-reducing gel as ~150 kDa band and upon reduction generates a ~25 kDa light chain band and a ~50 kDa heavy chain.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select optimal candidates for production.
Advantages of recombinant rabbit monoclonal antibodies:
- Better specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to larger rabbit immune repertoire
Target Information
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fibers in eukaryotes.
Two molecules of each core histone (H2A, H2B, H3, H4) form an octamer, around which approximately 146 bp of DNA is wrapped to form nucleosomes.
The linker histone H1 interacts with linker DNA between nucleosomes, aiding chromatin compaction into higher-order structures.
This gene is intronless, encodes a member of the histone H4 family, and its transcripts lack polyA tails, containing instead a palindromic termination element.
Located in the large histone gene cluster on chromosome 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: 700158_Histone_H2A_Q96QV6-1_Rabbit.svg, 700158_Histone_H2A_Q96QV6-1_Rabbit_PDP.jpeg)
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