Thermo Fisher Scientific RAP1A Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rabbit, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

synthetic peptide KYDPTIEDSYRKQVEVDC conjugated to KLH, corresponding to amino acids 31-48 of Human RAP1a. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:RAP1A,uniProtId:P62834-1,ncbiNodeId:9606,antigenRange:31-48,antigenLength:184,antigenImageFileName:PA1-29451_RAP1A_P62834-1_Rabbit.svg,antigenImageFileNamePDP:PA1-29451_RAP1A_P62834-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.95 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS

Contains

no preservative

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_1960314

Product Specific Information

It is expected to cross-react with zebrafish and C. elegans based on sequence homology of 100% and 94%, respectively.

PA1-29451 has been successfully used in Western blot applications where a band of 25 kDa is detected. Positive control: rat brain tissue extract.

Target Information

The product of this gene belongs to the family of RAS-related proteins. These proteins share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between RAP proteins and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. The product of this gene counteracts the mitogenic function of RAS because it can interact with RAS GAPs and RAF in a competitive manner. Two transcript variants encoding the same protein have been identified for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.