Thermo Fisher Scientific SOAT1 Polyclonal Antibody
SOAT1 단백질을 검출하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC(Paraffin)에서 사용 가능. 인간 및 랫트 반응성. 고순도의 Affinity chromatography 정제 및 액상 형태로 제공. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SOAT1 (Accession P35610), corresponding to amino acid residues F384–K434 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852290 |
Product Specific Information
Antibody detects endogenous levels of total SOAT1.
Target Information
SOAT1 (sterol O-acyltransferase-1), also designated ACAT1, is a homotetrameric enzyme that catalyzes the formation of cholesterol esters from cholesterol and long-chain fatty acyl-coenzyme A (acyl-CoA).
The human SOAT1 gene maps to chromosome 1 and encodes a protein localized to the endoplasmic reticulum (ER) in tissues such as liver, kidney, adrenal glands, and macrophages.
SOAT1 plays a key role in cholesterol homeostasis and foam cell formation, contributing to atherosclerosis progression.
SOAT2 (sterol O-acyltransferase-2), also known as ACAT2, catalyzes cholesterol esterification and is expressed in human intestinal cells. SOAT2 deficiency can lead to severe mental retardation and hypotonus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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