Thermo Fisher Scientific DAB2 Polyclonal Antibody
DAB2 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC(P), ICC/IF에 사용 가능. 인간 및 생쥐 시료 반응성. Affinity chromatography로 정제되었으며, PBS/glycerol buffer에 보관. 연구용 전용 제품.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human DAB2 (Accession P98082), corresponding to amino acid residues F738–A770 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852292 |
Product Specific Information
Antibody detects endogenous levels of total DAB2.
Target Information
DAB2 mRNA is expressed in normal ovarian epithelial cells but is down-regulated or absent from ovarian carcinoma cell lines.
The 770-amino acid predicted protein has an overall 83% identity with the mouse p96 protein, a putative mitogen-responsive phosphoprotein; homology is strongest in the amino-terminal end of the protein in a region corresponding to the phosphotyrosine interaction domain.
The down-regulation of DAB2 may play an important role in ovarian carcinogenesis.
This gene was initially named DOC2 (Differentially expressed in Ovarian Cancer) and is distinct from DOC2A and DOC2B genes (double C2-like domains, alpha and beta).
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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