Thermo Fisher Scientific CD263 (TRAIL-R3) Monoclonal Antibody (TRAIL-R3-02)
인간 TRAIL-R3(CD263)를 인식하는 Mouse IgG1 단일클론 항체입니다. Flow Cytometry에 적합하며, 단백질 A로 정제된 액상 형태입니다. PBS(pH 7.4) 버퍼에 보존제가 없으며 4°C에서 보관합니다. TRAIL 유도 세포사멸 연구에 유용합니다.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CD263 (TRAIL-R3) Monoclonal Antibody (TRAIL-R3-02)
Applications
- Flow Cytometry (Flow): 1–4 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | TRAIL-R3-02 |
| Immunogen | TRAIL-R3 (aa 1–280) - hIgGhc fusion protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1091005 |
Additional Formats
Product Specific Information
This antibody reacts with TRAIL-R3, a 35 kDa GPI-anchored extracellular membrane protein expressed mainly on neutrophils.
Target Information
TRAIL-R3 (CD263) is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. It does not induce apoptosis and functions as an antagonistic receptor protecting cells from TRAIL-induced apoptosis. This gene is p53-regulated and DNA damage-inducible, expressed in many normal tissues but not in most cancer cell lines, which may explain the selective sensitivity of cancer cells to TRAIL-induced apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.