Thermo Fisher Scientific IFNA2 Monoclonal Antibody (OTI12C7), TrueMAB
인간 IFNA2에 특이적인 마우스 단클론 항체로, Western blot에 최적화됨. 고순도 친화 크로마토그래피로 정제되고 PBS/BSA/glycerol 버퍼에 보존. 항바이러스 면역 연구 및 IFN 신호전달 분석에 적합.
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Applications
Tested Application and Dilution
- Western Blot (WB): 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI12C7 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 24–188 of human IFNA2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20 °C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
IFN alpha (Interferon alpha) is a Type I interferon belonging to a family of structurally related, species-specific proteins exclusive to vertebrates. The interaction of IFN-alpha with its receptor components results in the activation of signaling pathways involved in innate immune responses against viral infection.
In humans, the IFN alpha gene is located on chromosome 9. Type I interferons consist of 14 different alpha isoforms and single beta, omega, epsilon, and kappa isoforms. Homologous molecules are found across many species including mammals, birds, reptiles, and fish.
IFN alpha is mainly produced by plasmacytoid dendritic cells and plays a key role in antiviral innate immunity and modulation of adaptive immune responses. Dysfunction of IFN alpha has been associated with diseases such as Hepatitis C and Hepatitis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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