Thermo Fisher Scientific CARD9 Monoclonal Antibody (OTI3F8), TrueMAB
CARD9 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot에 적합. 인간 CARD9 전체 길이 재조합 단백질을 면역원으로 제작. 고순도 친화 크로마토그래피 정제, PBS/BSA/glycerol 완충액에 보관. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3F8 |
| Immunogen | Full-length human recombinant protein of CARD9 produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by the CARD9 gene belongs to the CARD protein family, characterized by the caspase-associated recruitment domain (CARD). This domain mediates protein-protein interactions involved in activation or suppression of caspase family members, playing a key regulatory role in apoptosis. CARD9 interacts selectively with the CARD domain of BCL10, a positive regulator of apoptosis and NF-κB activation, functioning as a scaffold for assembling the BCL10 signaling complex that activates NF-κB. Several alternatively spliced transcript variants have been identified, though their full-length structures are not clearly defined.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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