Thermo Fisher Scientific eIF3g Polyclonal Antibody
eIF3g 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, WB, IHC, ICC/IF, IP 등 다양한 응용에 적합합니다. 인간 및 마우스 반응성을 가지며, 합성 펩타이드 면역원 기반으로 제작되었습니다. 액상 형태로 −20°C에서 보관합니다.
- 카탈로그번호
- PA541774
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.2–1 µg/mL |
| Immunohistochemistry (IHC) | 1:500 |
| Immunocytochemistry (ICC/IF) | 1:500 |
| Immunoprecipitation (IP) | 1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human EIF3G |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2610012 |
Product Specific Information
- Peptide sequence: LRDGASRRGE SMQPNRRADD NATIRVTNLS EDTRETDLQE LFRPFGSISR
- Sequence homology: Cow: 100%; Dog: 100%; Goat: 86%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 100%
Target Information
The eIF3g protein is a component of the eukaryotic translation initiation factor 3 (eIF-3) complex, essential for multiple steps in the initiation of protein synthesis.
The eIF-3 complex associates with the 40S ribosome and facilitates recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi, and eIF-5 to form the 43S preinitiation complex (43S PIC).
It stimulates mRNA recruitment to the 43S PIC and scanning for AUG recognition, and is required for disassembly and recycling of posttermination ribosomal complexes, preventing premature joining of the 40S and 60S ribosomal subunits.
This subunit can bind 18S rRNA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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