Thermo Fisher Scientific eIF3b Polyclonal Antibody
Thermo Fisher Scientific의 eIF3b Polyclonal Antibody는 인간 eIF3b 단백질의 C-말단 펩타이드에 특이적인 토끼 다클론 항체입니다. Western blot에 적합하며, 높은 종간 서열 상동성을 보입니다. 액상 형태로 제공되며 -20°C에서 보관합니다.
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Thermo Fisher Scientific eIF3b Polyclonal Antibody
Applications
- Western Blot (WB): 0.2–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal of human EIF3S9 (aa 760–809) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2608473 |
Product Specific Information
- Peptide sequence: YRKMAQELYM EQKNERLELR GGVDTDELDS NVDDWEEETI EFFVTEEIIP
- Sequence homology:
Cow: 93% | Dog: 100% | Guinea Pig: 100% | Horse: 100% | Human: 100% | Mouse: 100% | Rabbit: 100% | Rat: 100% | Zebrafish: 100%
Target Information
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of initiation factors to form the 43S pre-initiation complex (43S PIC). It stimulates mRNA recruitment and scanning for AUG recognition, aids disassembly of post-termination ribosomal complexes, and prevents premature ribosomal subunit joining.
The eIF-3 complex specifically targets translation of mRNAs involved in cell proliferation, differentiation, and apoptosis. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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