Invitrogen™

Iodoacetamide Azide

Conjugates prepared with the thiol-reactive azide, succinimidyl ester can be detected with an alkyne-containing molecule in a click chemistry reaction.자세히 알아보기

Conjugates prepared with the thiol-reactive azide, succinimidyl ester can be detected with an alkyne-containing molecule in a click chemistry reaction. Click chemistry describes a class of chemical reactions that use bio-orthogonal or biologically unique moities to label and detect a molecule of interest using a two-step procedure. The two-step reaction procedure involves a copper-catalyzed triazole formation of an azide and an alkyne. Click reactions have several characteristics: the reaction between the detection moieties is efficient; no extreme temperatures or solvents are required; the reaction product is stable; the components of the reaction are bioinert; and perhaps most importantly, no side reactions occur – the label and detection tags react selectively and specifically with one another. Unlike traditional chemical reactions utilizing succinimidyl esters or maleimides that target amines and sulfhydryls – functional groups that are not unique – click chemistry-labeled molecules can be applied to complex biological samples and be detected with unprecedented sensitivity due to extremely low background.

사양

형식Solid

수량1 mg

제품 유형Iodoacetamide Azide

분자량310.14 Da

용해도DMSO (Dimethylsulfoxide)

화학물질 반응성Thiol

반응성 그룹Iodoacetamide

배송 조건Room Temperature

반응성 부분Alkyl Halide, Iodoacetamide

라벨 또는 염료Azide

라벨 유형Click Chemistry Label

제품라인Molecular Probes™

Unit SizeEach