Thermo Fisher Scientific DDX3 Polyclonal Antibody
인간, 생쥐, 랫트 시료에 반응하는 DDX3 폴리클로날 항체입니다. IHC(P)에서 1:50–1:200 희석 비율로 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며, 4°C 단기 보관 및 -20°C 장기 보관이 권장됩니다.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 291–340 of Human DDX3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2803098 |
Product Specific Information
- Purity is >95% by SDS-PAGE.
Target Information
The protein encoded by this gene is a member of the large DEAD-box protein family, defined by the conserved Asp-Glu-Ala-Asp (DEAD) motif, and exhibits ATP-dependent RNA helicase activity. It shows high RNA-independent ATPase activity, and unlike most DEAD-box helicases, its ATPase activity is stimulated by both RNA and DNA.
This protein functions in both the nucleus and cytoplasm, participating in transcriptional regulation, mRNP assembly, pre-mRNA splicing, mRNA export, translation, cellular signaling, and viral replication. Misregulation of this gene has been linked to tumorigenesis. It has a paralog on the Y chromosome, and pseudogenes are found on chromosome 4 and the X chromosome. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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