Thermo Fisher Scientific GABBR2 Recombinant Rabbit Monoclonal Antibody (23H5L12)
GABBR2 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot에 적합합니다. 높은 특이성과 민감도를 제공하며, 로트 간 일관성이 우수합니다. 인간 및 생쥐 반응성이 검증되었으며, 단기 4°C, 장기 -20°C 보관이 권장됩니다.
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Applications
- Western Blot (WB)
Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 23H5L12 |
| Immunogen | Peptide corresponding to human GABBR2 [aa318-aa333] |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2734810 |
Product Specific Information
This antibody is predicted to react with Monkey, Rat, and Dog.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.
Advantages of recombinant rabbit monoclonal antibodies:
- Better specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to larger rabbit immune repertoire
Target Information
The multi-pass membrane protein GABBR2 belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily.
GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, regulating neurotransmitter release, ion channel activity, and adenylyl cyclase.
GABBR2 forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective alone.
Allelic variants of this gene have been associated with nicotine dependence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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