Thermo Fisher Scientific MCHR1 Recombinant Rabbit Monoclonal Antibody (12H4L9)
MCHR1 단백질을 인식하는 재조합 토끼 단클론 항체로 높은 특이성과 감도를 제공함. WB, IHC, ICC/IF에 1:500 희석으로 사용 가능. Expi293 시스템에서 발현, Protein A로 정제됨. 동물 유래 성분이 없는 안정적 제형으로 연구용에 적합.
- 카탈로그번호
- 702618
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500 | - |
| Immunohistochemistry (IHC) | 1:500 | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:500 | - |
Product Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human, Rat |
| Published Species | Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 12H4L9 |
| Immunogen | Peptide corresponding to human MCHR1 [aa401-aa422] |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2734816 |
Product Specific Information
This antibody is predicted to react with Monkey, Mouse, and Rabbit.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select optimal candidates for production.
Advantages of recombinant rabbit monoclonal antibodies:
- Better specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to larger rabbit immune repertoire
Target Information
MCHR1 is a member of the G protein-coupled receptor family 1. It is an integral plasma membrane protein that binds melanin-concentrating hormone. The encoded protein can inhibit cAMP accumulation and stimulate intracellular calcium flux, and is likely involved in neuronal regulation of food consumption. Although structurally similar to somatostatin receptors, MCHR1 does not bind somatostatin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지: 702618_MCHR1_Q99705-1_Rabbit.svg, 702618_MCHR1_Q99705-1_Rabbit_PDP.jpeg)
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