Thermo Fisher Scientific MSK1 Recombinant Rabbit Monoclonal Antibody (4H15L51)

Applications

Western Blot (WB)

• Tested Dilution: 1–2 µg/mL

Immunocytochemistry (ICC/IF)

• Tested Dilution: 2 µg/mL

Product Specifications

Product Specific Information

This antibody is predicted to react with Monkey, Pig, Rat, and Mouse.

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. These systems clone specific antibody DNA sequences from immunoreactive rabbits, and individual clones are screened to select optimal production candidates.

Advantages of recombinant rabbit monoclonal antibodies:

• Superior specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulation
• Broader immunoreactivity due to larger rabbit immune repertoire

Target Information

RPS6KA5 (MSK1) is a serine/threonine protein kinase essential for regulating various cellular processes.
It is required for mitogen- or stress-induced phosphorylation of transcription factors CREB1 and ATF1, and regulates RELA, STAT3, and ETV1/ER81.
MSK1 contributes to gene activation via histone phosphorylation and controls inflammatory gene expression.
In skeletal myoblasts, it mediates RELA phosphorylation at Ser-276 during oxidative stress, and in erythropoietin-stimulated cells, it regulates STAT3 phosphorylation at Ser-727.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지

(이미지 파일명: 702653_MSK1_O75582-1_Rabbit_PDP.jpeg)