Thermo Fisher Scientific Setdb2 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:10,000–1:100,000

ELISA

• Tested Dilution: 1:2,500–1:10,000

Product Specifications

Product Specific Information

• Store vial at -20°C prior to opening.
• Aliquot contents and freeze at -20°C or below for extended storage.
• Avoid cycles of freezing and thawing.
• Centrifuge product if not completely clear after standing at room temperature.
• Stable for several weeks at 4°C as an undiluted liquid.
• Dilute only prior to immediate use.
• This Protein A purified antibody is directed against mouse Setdb2.
• Expected reactivity with Setdb2 from mouse and human sources; reactivity with homologues from other species is not known.

Target Information

Proteins that contain a SET domain, such as SETDB2, modulate gene expression epigenetically through histone H3 methylation. SETDB2 is likely a histone H3 methyltransferase, as it contains both the active site and flanking cysteine residues required for catalytic activity (Zhang et al., 2003).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.