Thermo Fisher Scientific CLIC1 Polyclonal Antibody
Human CLIC1 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, ELISA, IP에 사용 가능. Protein A 정제 및 액상 형태로 제공되며, -20°C 보관. 인간, 설치류, 소 등에서 높은 상동성 확인.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1 µg/mL | - |
| ELISA (ELISA) | Assay-dependent | - |
| Immunoprecipitation (IP) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | This protein A purified antibody was prepared from whole rabbit serum produced by repeated immunizations with human CLIC1 recombinant protein. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.06 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.02M potassium phosphate, pH 7.2, with 0.15M NaCl |
| Contains | 0.01% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use.
This antibody is specific for human CLIC1. BLAST analysis indicates cross-reactivity with:
- Human: 100% homology (immunizing sequence)
- Rat and Mouse: 98% homology
- Bovine and Oryctolagus cuniculus: 97% homology
Cross-reactivity with other species has not been determined.
Target Information
Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including:
- Stabilization of cell membrane potential
- Transepithelial transport
- Maintenance of intracellular pH
- Regulation of cell volume
Chloride intracellular channel 1 (CLIC1) is a member of the p64 family. The protein localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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