Thermo Fisher Scientific ANGPTL7 Polyclonal Antibody

Applications

• Western Blot (WB): 0.2–1 µg/mL

Product Specifications

Product Specific Information

• Immunogen sequence: NQIDIMQLQA AQTVTQTSAD AIYDCSSLYQ KNYRISGVYK LPPDDFLGSP
• Storage recommendations:
  • Short-term: 2–8°C (up to 1 week)
  • Long-term: -20°C in small aliquots to prevent freeze-thaw cycles
• Predicted homology:
  Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 93%; Rat: 100%

Target Information

Angptl7 (angiopoietin-like 7), also known as cornea-derived transcript 6 protein (CDT6) or AngX, is a 346 amino acid secreted protein expressed in the stromal layer of the cornea. It forms disulfide-linked homotetramers via coiled-coil interactions and contains one fibrinogen C-terminal domain. Overexpressed in glaucoma patients, Angptl7 is a potential therapeutic target and is known to increase collagen expression. The ANGPTL7 gene is located on human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes, and accounts for approximately 8% of the human genome.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.