Thermo Fisher Scientific NR1I3 Monoclonal Antibody (OTI9E1), TrueMAB
NR1I3 단백질을 인식하는 Mouse monoclonal antibody로, Western blot에 최적화되어 있습니다. Human 시료에 반응하며, 동결건조 형태로 제공됩니다. PBS buffer에 trehalose가 포함되어 안정성이 우수합니다. 연구용으로 xenobiotic 대사 조절 연구에 활용 가능합니다.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI9E1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–236 of human NR1I3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve an antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The NR1I3 gene encodes a member of the nuclear receptor superfamily and is a key regulator of xenobiotic and endobiotic metabolism.
This protein binds DNA as a monomer or heterodimer with the retinoid X receptor, regulating transcription of genes involved in drug metabolism and bilirubin clearance (e.g., cytochrome P450 family).
Unlike most nuclear receptors, this transcriptional regulator is constitutively active in the absence of ligand but can be modulated by agonists and inverse agonists.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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