Thermo Fisher Scientific SERPINC1 Monoclonal Antibody (435CT4.7.4)

Applications

• Western Blot (WB): 1:100–1:500 dilution

Product Specifications

Target Information

The protein encoded by the SERPINC1 gene is a plasma protease inhibitor and a member of the serpin superfamily.
It inhibits thrombin and other activated serine proteases of the coagulation system, regulating the blood coagulation cascade.
This protein includes two functional domains:

• Heparin binding domain at the N-terminus
• Reactive site domain at the C-terminus

Its inhibitory activity is enhanced by the presence of heparin.
Over 120 mutations have been identified, many causing antithrombin-III deficiency.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.