Thermo Fisher Scientific CX3CR1 Polyclonal Antibody
CX3CR1 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC, Flow Cytometry 등 다양한 응용에 사용 가능. 항원 친화 정제 방식으로 제조되었으며, Human 시료에 반응. 1 mg/mL 농도의 액상 형태로 제공.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.5–1 µg/mL | - |
| Immunohistochemistry (IHC) | - | View 2 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2 µg/mL | - |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 2 µg/mL | - |
| Immunocytochemistry (ICC/IF) | 10–20 µg/mL | - |
| Flow Cytometry (Flow) | 0.1 µg/mL | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A peptide corresponding to amino acids 2–21 of human CX3CR1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at –20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11154568 |
Product Specific Information
- In Western blot applications, this antibody detects a band at approximately 50 kDa.
- Suggested positive control: human spleen tissue lysate.
- PA5-19910 can be used with blocking peptide PEP-0036.
Target Information
CX3CR1 is a chemokine receptor required as a coreceptor for HIV infection. The genes encoding CX3CR1 in human, mouse, and rat were cloned and designated V28, CMKBRL1, CX3CR1, and RBS11, respectively.
The encoded seven-transmembrane protein acts as the receptor for the transmembrane molecule fractalkine and was renamed CX3CR1.
CX3CR1 serves as a coreceptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by fractalkine.
It mediates leukocyte migration and adhesion and is expressed in various human tissues and cell lines.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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