Thermo Fisher Scientific CCR8 Polyclonal Antibody
Human CCR8 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot에서 약 50kDa 밴드 검출에 사용됩니다. 항원 친화 크로마토그래피로 정제되었으며, PBS에 0.02% sodium azide가 포함된 액상 형태입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5 µg/mL |
Suggested Positive Control: Human spleen tissue lysate
Blocking Peptide: PEP-0037
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 19 amino acid peptide near the center of human CCR8 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.0 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long term storage store at -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11153934 |
Product Specific Information
In Western blot applications, this antibody detects a band at approximately 50 kDa.
A suggested positive control is human spleen tissue lysate.
PA5-19911 can be used with blocking peptide PEP-0037.
Target Information
CCR8 encodes a member of the beta chemokine receptor family, predicted to be a seven-transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are crucial for cell migration to inflammatory sites. This receptor is preferentially expressed in the thymus, and its ligands include I-309, TARC, and MIP-1β.
CCR8 plays a role in monocyte chemotaxis and thymic cell apoptosis, contributing to the positioning of activated T cells within antigenic challenge sites and lymphoid tissues. Expression has been reported in spleen, thymus, NK cells, monocytes, T cells, and at lower levels in peripheral blood leukocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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