Thermo Fisher Scientific Human PPAPDC3 Synthetic Peptide
인간 PPAPDC3 아미노 말단 19개 아미노산 서열 기반 합성 펩타이드. 항체 PA5-20866과 함께 차단 펩타이드로 사용 가능. 인간 단백질 반응성, 액상 형태, PBS 버퍼에 보존. 연구용으로만 사용.
- 카탈로그번호
- PEP0980
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 19 amino acids near the amino terminus of human PPAPDC3.
PEP-0980 can be used as a blocking peptide with polyclonal antibody PA5-20866.
Target Information
PPAPDC3, also known as nuclear envelope transmembrane protein 39 (NET39), was initially discovered in an in silico screen for secreted or membrane proteins. It belongs to the PAP2 superfamily of phosphatases and haloperoxidases. PPAPDC3 acts as a negative regulator of myoblast differentiation by diminishing the activity of the mammalian target of rapamycin (TOR). It is highly expressed in cardiac and skeletal muscle and becomes strongly upregulated during cultured myoblast differentiation. Overexpression of PPAPDC3 represses myogenesis, while knockdown by RNA interference promotes differentiation, indicating its role in the regulatory mechanism of myogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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