Thermo Fisher Scientific Human PPAPDC1A Synthetic Peptide
인간 PPAPDC1A 단백질의 카복시 말단 13개 아미노산 서열을 기반으로 한 합성 펩타이드. PA5-20864 항체의 블로킹 펩타이드로 사용 가능. 지질 신호 대사 연구 및 인체 내 PAP 활성 분석에 적합. 연구용으로만 사용.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 13 amino acids near the carboxy terminus of human PPAPDC1A.
PEP-0978 can be used as a blocking peptide with polyclonal antibody PA5-20864.
Target Information
Phosphatidate phosphatase (PAP) plays an important role in lipid-signaling metabolism in eukaryotic cells. Two distinct types of PAP (PAP1 and PAP2) activity have been distinguished by their subcellular localization and differential sensitivity to N-ethylmaleimide (NEM) and Mg²⁺.
A yeast diacylglycerol pyrophosphate (DGPP) phosphatase (DPP1) and mammalian DGPP phosphatase (PAP2) have been identified as Mg²⁺-independent and NEM-insensitive membrane-associated enzymes.
PPAPDC1A (also known as DPPL2) and PPAPDC1B (DPPL1) form a novel type of Mg²⁺-independent and NEM-sensitive mammalian phosphatidate phosphatase showing broad substrate specificity.
PPAPDC1A is preferentially expressed in endothelial cells. Studies of PPAPDC1A and PAP activity suggest that they may play a role in angiogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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