Thermo Fisher Scientific VRK2 Monoclonal Antibody (OTI8H5), TrueMAB
인간 VRK2 단백질을 표적으로 하는 마우스 단클론 항체. Western blot에 적합하며, 고순도 친화 크로마토그래피로 정제됨. 동결건조 형태로 제공되며, 재구성 후 약 1 mg/mL 농도로 사용 가능. 연구용으로 세포 내 VRK2 발현 분석에 유용.
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8H5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 301–486 of human VRK2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | −20 °C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882) to ensure carrier-free conditions.
Target Information
VRK2 (vaccinia-related kinase 2) is a serine/threonine kinase belonging to the VRK family. It is widely expressed in human tissues and is highly abundant in actively dividing cells such as those in the testis, leukocytes, fetal liver, and various carcinomas.
VRK2 can phosphorylate casein and undergo autophosphorylation. It interacts with the Epstein–Barr virus BHRF1 protein (a Bcl-2 homologue), contributing to cellular protection from apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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