Thermo Fisher Scientific CD41 Monoclonal Antibody (MEM-06), Biotin
인간 CD41(GPIIb) 항원을 인식하는 Mouse IgG1 단일클론 항체로, Biotin으로 표지됨. Flow Cytometry에 적합하며, 혈소판 및 거대핵세포 표지에 유용. 4°C 보관, PBS(pH 7.4) 버퍼와 sodium azide 포함.
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Applications
- Flow Cytometry (Flow): Tested dilution 2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MEM-06 |
| Immunogen | Leucocytes from a patient suffering from a LGL type leukaemia |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1075436 |
Additional Formats
Product Specific Information
This antibody reacts with an extracellular epitope of CD41 (GPIIb), a transmembrane glycoprotein (integrin family) composed of two chains: GPIIb alpha (heavy chain; 120 kDa) and GPIIb beta (light chain; 23 kDa). CD41 is mainly expressed on platelets and megakaryocytes.
Target Information
CD41 (platelet glycoprotein IIb, ITGA2B) forms a functional adhesive receptor with CD61 in the presence of calcium. It mediates platelet aggregation and binds to von Willebrand factor, fibrinogen, fibronectin, and vitronectin upon vascular injury. CD41 is expressed on megakaryocyte-platelet lineage and during early hematopoietic differentiation.
Diseases associated with CD41 dysfunction include Glansmann Thrombasthenia and Platelet type-16 bleeding disorder.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송/결제/교환/반품 안내
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