Thermo Fisher Scientific eIF2B delta/EIF2B4 Polyclonal Antibody
Rabbit polyclonal antibody targeting human EIF2B4 (eIF2B delta subunit). Validated for WB, IHC, IHC-P, and IP applications. Unconjugated, liquid form, concentration 0.20 mg/mL. Recommended storage at 4°C; shelf life 1 year. For research use onl...
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Thermo Fisher Scientific eIF2B delta/EIF2B4 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:200–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200–1:1,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 50 and 100 of human Eukaryotic Translation Initiation Factor 2B, Subunit 4 delta (67 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections
Target Information
Eukaryotic initiation factor 2B (EIF2B) is a GTP exchange factor essential for protein synthesis, composed of five subunits. The encoded protein is the delta (EIF2B4) subunit. Mutations in this gene are associated with leukoencephalopathy with vanishing white matter (VWM) and ovarioleukodystrophy. Multiple transcript variants encoding different isoforms have been identified.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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