
Thermo Fisher Scientific MBP Polyclonal Antibody
Western blot과 IHC(Paraffin)에서 검증된 MBP 폴리클로날 항체. Rabbit에서 생산된 Ig 형태로, Human, Mouse, Rat에 반응. 동결건조 형태로 제공되며, 장기보관 시 -20°C에서 안정적. 신경계 미엘린 수초 단백질 연구에 적합.
- 카탈로그번호
- OSM00141W-100UL
- 판매단위
- pk
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:2,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000 | - |
| Miscellaneous PubMed (Misc) | - | View 2 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from human MBP conjugated to blue carrier protein was used as the antigen |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: MBP.
Target Information
The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. MBP-related transcripts are also present in the bone marrow and immune system. These mRNAs arise from the long MBP gene (Golli-MBP), which contains additional upstream exons. Alternative splicing from the Golli and MBP transcription start sites produces two sets of MBP-related transcripts and proteins.
Golli mRNAs contain three exons unique to Golli-MBP, spliced in-frame to one or more MBP exons, encoding hybrid proteins with N-terminal Golli and MBP amino acid sequences. The second transcript family contains only MBP exons, producing the well-characterized myelin basic proteins. This conserved gene structure among species suggests that the MBP transcription unit is part of the Golli transcription unit, important for gene function and/or regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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