Thermo Fisher Scientific S100B Polyclonal Antibody
S100B 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC, IP 등 다양한 응용에 사용 가능. Rat brain lysate를 양성 대조군으로 권장하며, 0.65 mg/mL 농도의 액상 형태로 제공. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1:500 | |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent | |
| Immunocytochemistry (ICC/IF) | Assay-dependent | |
| Immunoprecipitation (IP) | 1:250 |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Full length native protein homodimer (purified) (Human) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.65 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2184563 |
Product Specific Information
Positive control of rat brain tissue lysate suggested.
Target Information
S100B is a member of the S100 family of proteins containing two EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells and are involved in the regulation of cellular processes such as cell cycle progression and differentiation.
S100B may function in neurite extension, proliferation of melanoma cells, stimulation of Ca²⁺ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several diseases, including Alzheimer’s disease, Down’s syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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