Thermo Fisher Scientific CD11c Monoclonal Antibody (N418), PE-Cyanine5, eBioscience
마우스 CD11c 표적화 단일클론 항체로 PE-Cyanine5 형광 접합. Flow cytometry에 최적화되어 있으며 0.5 µg/test 권장. 488–561 nm 여기, 667 nm 방출. 4°C 암소 보관, 연구용 전용.
- 카탈로그번호
- 15-0114-8x (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CD11c Monoclonal Antibody (N418), PE-Cyanine5, eBioscience
Applications
Immunohistochemistry (Frozen) (IHC (F))
- Tested Dilution: -
- Publications: View 2 publications
Flow Cytometry (Flow)
- Tested Dilution: 0.5 µg/test
- Publications: View 138 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Human, Mouse |
| Host / Isotype | Armenian hamster / IgG |
| Recommended Isotype Control | Armenian Hamster IgG Isotype Control (eBio299Arm), PE-Cyanine5, eBioscience™ |
| Class | Monoclonal |
| Type | Antibody |
| Clone | N418 |
| Conjugate | PE-Cyanine5 |
| Excitation / Emission Max | 568 / 666 nm |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_468716 |
Additional Formats Available
- Unconjugated
- Alexa Fluor 488
- Alexa Fluor 532
- Alexa Fluor 660
- Alexa Fluor 700
- APC
- APC-eFluor 780
- Biotin
- Brilliant UV 395, 496, 563, 615, 661, 737, 805
- Brilliant Violet 421, 605, 650, 711
- eFluor 450, 506, 615, 660
- FITC
- Functional Grade
- NovaFluor Blue 510, 610-30S, 660-40S, 690
- NovaFluor Yellow 570
- PE
- PE-Cyanine5.5
- PE-Cyanine7
- PE-eFluor 610
- PerCP-Cyanine5.5
- Super Bright 436, 600, 645, 780
- Request custom conjugation
Product Specific Information
The N418 monoclonal antibody reacts with mouse CD11c, the integrin alpha X. CD11c associates with beta 2 integrin to form the CD11c/CD18 heterodimer, expressed by dendritic cells, intestinal intraepithelial lymphocytes, and activated T cells. It binds to CD54, iC3b, and fibrinogen, playing a role in leukocyte adhesion.
Applications Reported: Flow cytometric analysis.
Applications Tested: Mouse splenocytes, ≤0.5 µg/test (100 µL volume). Optimize empirically for best performance.
- Light sensitivity: Protect from light to prevent photo-induced oxidation.
- Fixation: Can be stored up to 3 days at 4°C in IC Fixation Buffer (Product #00-822-49) or 1-step Fix/Lyse Solution (Product #00-5333-54).
- Excitation: 488–561 nm
- Emission: 667 nm
- Laser Compatibility: Blue, Green, Yellow-Green
- Filtration: 0.2 µm post-manufacturing filtered.
Target Information
CD11, together with CD18, forms a heterodimer adhesion molecule.
- CD11a: Expressed in B/T lymphocytes, macrophages, monocytes, neutrophils, basophils, eosinophils.
- CD11b: Expressed in monocytes, macrophages, NK cells, some B/T cells, granulocytes.
- CD11c: Expressed in monocytes, macrophages, NK cells, some granulocytes, and subsets of lymphocytes.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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