Thermo Fisher Scientific Cell-Surface Vimentin (CSV) Monoclonal Antibody (84-1), Biotin
인간 세포 표면 비멘틴을 인식하는 단클론 항체로, Biotin으로 표지되어 있습니다. ICC/IF 및 유세포분석(Flow Cytometry)에 적합하며, 고순도 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 10–100 µg/mL |
| Flow Cytometry (Flow) | 1×10⁶ cells / 50 µL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 84-1 |
| Immunogen | Human recombinant vimentin |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -80°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Dry ice |
Additional Formats
Target Information
Vimentin is a developmentally regulated intermediate filament protein (IFP) found in cells of mesenchymal origin. It is believed to be involved in intracellular transport of proteins between the nucleus and plasma membrane. Unlike other IFPs, vimentin is co-expressed with desmin during early cellular development, and later replaced by tissue-specific IFPs. Vimentin also plays a role in steroid synthesis by acting as a storage network for cholesterol-containing lipid droplets. Phosphorylation of vimentin by protein kinase leads to filament breakdown and cytoskeletal rearrangements, facilitating cholesterol transport to mitochondria and enhancing steroidogenesis.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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