Thermo Fisher Scientific RhoG Polyclonal Antibody

Applications and Tested Dilutions

Product Specifications

Product Specific Information

Immunogen sequence:
TVNLNLWDTA GQEEYDRLRT LSYPQTNVFV ICFSIASPPS YENVRHKWHP EVCHHCPDVP ILLVGTKKDL RAQPDTLRRL KEQGQAPITP QQGQALAKQI H

Target Information

The Ras p21 family of guanine nucleotide proteins has been widely studied for its role in signal transduction and its frequent mutations in human malignancies. Ras proteins (H-, K-, and N-Ras p21) belong to a larger superfamily of related proteins. Six members—Rap 1A, Rap 1B, Rap 2, R-Ras, Ral A, and Ral B—show approximately 50% amino acid homology to Ras. The six mammalian Rho proteins (Rho A, B, C, G, 7, and 8) are about 30% homologous to Ras and are expressed in various cell types. Both Ras p21 and Rho p21 contain a carboxy-terminal CAAX sequence (C: cysteine; A: aliphatic amino acid; X: any amino acid), which is essential for proper localization and function.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.