Thermo Fisher Scientific DLC1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 204-463 of human DLC1 (NP_079043.3). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:DLC1,uniProtId:Q96QB1-2,ncbiNodeId:9606,antigenRange:204-463,antigenLength:1528,antigenImageFileName:PA5-120668_DLC1_Q96QB1-2_Rabbit.svg,antigenImageFileNamePDP:PA5-120668_DLC1_Q96QB1-2_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.58 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2914240

Product Specific Information

Positive test controls include: Mouse lung. The target is usually found in the following locations: Cell junction, Cytoplasm, Membrane, Peripheral membrane protein, focal adhesion.

Immunogen sequence: DAPKVNAVDT LNVKDIAPEK QLLNSAVIAQ QRRKPDPPKD ENERSTCNVV QNEFLDTPCT NRGLPLLKTD FGSCLLQPPS CPNGMSAENG LEKSGFSQHQ NKSPPKVKAE DGMQCLQLKE TLATQEPTDN QVRLRKRKEI REDRDRARLD SMVLLIMKLD QLDQDIENAL STSSSPSGTP TNLRRHVPDL ESGSESGADT ISVNQTRVNL SSDTESTDLP SSTPVANSGT KPKTTAIQGI SEKEKAGKLT FWFCFLANLF

Target Information

This gene encodes a GTPase-activating protein that is a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins. GAP family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. This gene functions as a tumor suppressor gene in a number of common cancers, including prostate, lung, colorectal, and breast cancers. Multiple transcript variants due to alternative promoters and alternative splicing have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.