Thermo Fisher Scientific CD1a/HTA1 (Mature Langerhans Cells Marker) Monoclonal Antibody (O10)
CD1a 단백질을 인식하는 O10 클론의 mouse monoclonal antibody로, 인간 및 원숭이 시료에 반응합니다. WB, IHC, ICC, Flow Cytometry 등 다양한 응용에 적합하며, Protein A/G로 정제된 액상 형태로 제공됩니다. 4°C에서 보관하며 동결 금지.
- 카탈로그번호
- 909-MSM1-Px (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CD1a/HTA1 (Mature Langerhans Cells Marker) Monoclonal Antibody (O10)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Rhesus monkey |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | O10 |
| Immunogen | Human thymus cells (Target: CD1a, UniProt ID: P06126-1, Antigen range: 1–327) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CD1a is a non-polymorphic MHC Class I–related cell surface glycoprotein expressed in association with β2-microglobulin. It is found on cortical thymocytes, Langerhans cells, and interdigitating dendritic cells. CD1a is also expressed in certain T-cell malignancies and histiocytosis X.
Structurally related to MHC proteins, CD1a forms heterodimers with β2-microglobulin and mediates lipid and glycolipid antigen presentation to T cells.
The human genome contains five CD1 family genes (CD1a, b, c, d, e) located on chromosome 1. These family members differ in cellular localization and ligand specificity. CD1a localizes to the plasma membrane and early endocytic vesicles. Alternatively spliced transcript variants have been observed, though their biological significance remains unclear.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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