Thermo Fisher Scientific MAP2K4 Polyclonal Antibody
MAP2K4 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC, IP 등 다양한 응용에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 고순도(>95%)와 안정적인 액상 형태로 제공됩니다.
- 판매단위
- pk
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Thermo Fisher Scientific MAP2K4 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Immunoprecipitation (IP) | 1:10–1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 330–380 of Human MEK-4 (MAP2K4) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2803215 |
Product Specific Information
Purity is >95% by SDS-PAGE.
Target Information
MAP2K4 (MEK4) is a serine/threonine kinase of the STE7 family that phosphorylates and activates JNK1/2 and p38. It preferentially phosphorylates the tyrosine residue of JNKs and mediates various physiological and pathophysiological processes such as cellular stress and inflammatory responses. MAP2K4 is implicated in carcinogenesis, with loss-of-function mutations found in lung and pancreatic tumors, while pro-oncogenic roles have also been reported.
Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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