Thermo Fisher Scientific CDK2 Polyclonal Antibody
CDK2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC(Paraffin) 실험에 적합. 고순도(>95%) 항원 친화 크로마토그래피 정제. Human, Mouse, Rat 반응성. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 230–278 of Human CDK2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C (avoid freeze/thaw cycles) |
| Shipping Conditions | Wet ice |
| RRID | AB_2803213 |
Product Specific Information
Purity is >95% by SDS-PAGE.
Target Information
CDK2/cyclinO is a member of the cyclin-dependent protein kinase family complexed to CyclinO. CyclinO was used as a specific protein isoform name for the UNG gene, localized exclusively in the nucleus, and shows significant uracil-DNA glycosylase activity.
CDK2/cyclinO protein levels increase during G1 phase and are turned over during the cell cycle. Cyclin A-CDK2 levels are maximal at the G1/S transition and both CDK2 and Cyclin A are associated with DNA in the initiation complex during replication.
Rb protein acts as a substrate for CDK2-Cyclin E and/or CDK2-Cyclin A in vivo. CDK2 is activated and localized to the nucleus during late G1, S, and G2 phases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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