Thermo Fisher Scientific CKMT2 Polyclonal Antibody
Rabbit polyclonal antibody against CKMT2 for IHC and ICC applications. Reacts with human, mouse, and rat. High purity (>95%) and antigen affinity purified. Supplied in PBS with 50% glycerol, suitable for research use only.
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- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 230–280 of Human CKMT2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2803211 |
Product Specific Information
Purity is >95% by SDS-PAGE.
Target Information
Mitochondrial creatine kinase (MtCK) is responsible for transferring high-energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family and exists as two isoenzymes: sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two oligomeric forms, dimers and octamers, unlike the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric MtCK shares 80% homology with ubiquitous MtCK. This gene includes sequences homologous to nuclear genes encoding mitochondrial proteins, potentially important for coordinated activation during mitochondrial biogenesis. Three transcript variants encoding the same protein have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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