Thermo Fisher Scientific CX3CL1 Polyclonal Antibody
CX3CL1 단백질을 인식하는 염소 유래 폴리클로날 항체로, 인간 시료에 반응합니다. Western blot과 Peptide ELISA에 적합하며, 0.5 mg/mL 농도의 액상 형태입니다. 신경독성 억제 및 면역세포 이동 연구에 활용됩니다.
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Thermo Fisher Scientific CX3CL1 Polyclonal Antibody
Applications
- Western Blot (WB): 0.3–1 µg/mL
- Peptide ELISA: Antibody detection limit dilution 1:128,000
Publications
- [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-KTSEAPSTQDPST |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933819 |
Target Information
Chemokines are a family of proteins associated with leukocyte trafficking during immune surveillance and inflammatory responses. CX3CL1, a CX3C chemokine, mediates adhesion and migration of leukocytes via membrane-bound and soluble forms. Studies indicate that CX3CL1 may suppress production of nitrous oxide, interleukin-6, and TNF-α in activated microglia and neuronal cells, suggesting a role as an intrinsic inhibitor against neurotoxicity. Its receptor, CX3CR1, also acts as a co-receptor for HIV-1 and HIV-2 envelope fusion and infection, which can be inhibited by CX3CL1.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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