Thermo Fisher Scientific GLRX Polyclonal Antibody
Thermo Fisher Scientific의 GLRX Polyclonal Antibody는 mouse Glutaredoxin 1을 인식하는 goat polyclonal 항체입니다. Western blot에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. Lyophilized 형태로 제공되며, -20°C에서 보관합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived recombinant mouse Glutaredoxin 1 (Met1–Leu107) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2576816 |
Product Specific Information
This antibody detects endogenous human and mouse Glutaredoxin in Western blots.
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
Glutaredoxin (Grx), also known as thiol transferase, is a small heat-stable oxidoreductase.
Grxs form part of the glutaredoxin system, comprising NADPH, GSH, and glutathione reductase, which transfers electrons from NADPH to glutaredoxins via GSH.
First recovered in E. coli as GSH-dependent hydrogen donors for ribonucleotide reductase, Grx catalyzes GSH-disulfide oxidoreductase via two redox-active cysteine residues.
The active sequence (Cys-Pro-Tyr-Cys) is conserved in a variety of species.
The 12-kDa dithiol protein plays a role in reduction of mixed disulfides in cells exposed to oxidative stress.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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