Thermo Fisher Scientific GLRX Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 0.5 µg/mL

Product Specifications

Product Specific Information

This antibody detects endogenous human and mouse Glutaredoxin in Western blots.
Reconstitute at 0.2 mg/mL in sterile PBS.

Target Information

Glutaredoxin (Grx), also known as thiol transferase, is a small heat-stable oxidoreductase.
Grxs form part of the glutaredoxin system, comprising NADPH, GSH, and glutathione reductase, which transfers electrons from NADPH to glutaredoxins via GSH.
First recovered in E. coli as GSH-dependent hydrogen donors for ribonucleotide reductase, Grx catalyzes GSH-disulfide oxidoreductase via two redox-active cysteine residues.
The active sequence (Cys-Pro-Tyr-Cys) is conserved in a variety of species.
The 12-kDa dithiol protein plays a role in reduction of mixed disulfides in cells exposed to oxidative stress.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.