Thermo Fisher Scientific CD22 Monoclonal Antibody (MEM-01), Biotin
CD22 단백질을 인식하는 Biotin 결합 단클론 항체로, Western blot, Flow cytometry, Immunoprecipitation에 사용 가능. 인간 및 비인간 영장류 반응성. PBS 완충액 내 1 mg/mL 농도, 4°C 보관. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Flow Cytometry (Flow) | 1–3 µg/mL |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MEM-01 |
| Immunogen | Burkitt’s lymphoma cell line Raji |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1071665 |
Additional Formats
Product Specific Information
This antibody recognizes a unique epitope “E” and does not cross-block antibodies RFB-4, CLB22/1, and CLB-BLy1.
Target Information
CD22 (BL-CAM) is a type I integral membrane glycoprotein (130–140 kDa) expressed in the cytoplasm and membrane of B-lymphocytes.
It appears early in B-cell differentiation, similar to CD19, and is expressed in mature B cells but not plasma cells.
CD22 is useful in phenotyping mature leukemias and is strongly expressed in hairy cell leukemia, diffuse large B-cell lymphoma, and nodular lymphocyte predominance Hodgkin’s lymphoma, but negative in classical Hodgkin’s lymphoma.
It preferentially binds α2,6-linked sialic acid and participates in regulation of B-cell receptor signaling via interactions with Src family kinases and cytoplasmic phosphatases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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