Thermo Fisher Scientific EZH2 Monoclonal Antibody (144CT2.1.1.5)
EZH2 단백질을 인식하는 Mouse monoclonal antibody로, Western blot, IHC, ICC, ChIP 등 다양한 응용에 적합. Human 시료에 반응하며, Protein G 정제 및 PBS buffer에 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:2,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:25 | - |
| Immunocytochemistry (ICC/IF) | 1:25 | View 1 publication |
| ChIP assay (ChIP) | 4 µL/10^6 cells | - |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 144CT2.1.1.5 |
| Immunogen | EZH2 recombinant protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2539482 |
Product Specific Information
This antibody is predicted to react with non-human primate based on sequence homology.
Target Information
EZH2 (Histone-lysine N-methyltransferase) is a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. EZH2 may play a role in hematopoietic and central nervous systems. Mutations affecting EZH2 can cause Weaver syndrome (WVS).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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