Thermo Fisher Scientific TSLP Receptor Polyclonal Antibody
TSLP 수용체를 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, 인간·마우스·랫트 반응성. Western blot에 적합하며 고순도(>95%) 항원 친화 크로마토그래피로 정제됨. 장기 보관 시 -20°C에서 안정적이며 연구용으로 사용.
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Thermo Fisher Scientific TSLP Receptor Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:200–1:1,000
Publications: - [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein of human CRLF2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2803777 |
Product Specific Information
Purity is > 95% by SDS-PAGE.
Target Information
Thymic stromal lymphopoietin (TSLP) is an important factor that drives dendritic cell maturation and activation. It plays a role in the positive selection of regulatory T cells, maintenance of peripheral CD4+ T cell homeostasis, and induction of CD4+ T cell-mediated allergic reactions.
TSLP supports the growth and differentiation of fetal liver and adult B cell progenitors to the IgM-positive stage.
Its receptor, TSLP-R, binds TSLP with low affinity in transfected cells; co-transfection with IL-7R-alpha cDNA results in high-affinity binding and formation of a functional heteromeric complex.
This receptor complex requires STAT5 for TSLP-mediated signal transduction and is inhibited by SOCS-1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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