Thermo Fisher Scientific IL17RB Polyclonal Antibody
IL17RB 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Human, Mouse, Rat에 반응합니다. Western blot에 적합하며, 고순도(>95%) 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:4,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein of human IL17RB |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2803783 |
Product Specific Information
Purity is >95% by SDS-PAGE.
Target Information
A number of cytokines belonging to the interleukin (IL)-17 family have been identified, including IL-17B, IL-17C, and IL-17E. IL-17 is a potent proinflammatory cytokine involved in diseases such as rheumatoid arthritis, multiple sclerosis, and tumor growth promotion. IL-17B, C, and E can induce proinflammatory responses but do not bind to the IL-17 receptor, suggesting additional IL-17R-related receptors may exist.
Receptors for IL-17B and IL-17E have been identified as EV127 (mouse) and IL-17Rh1 (human), respectively. IL-17E activates the NF-κB pathway and induces IL-8 production. IL-17Rh1 mRNA is highly expressed in kidney and liver, with moderate levels in small intestine, colon, and brain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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