Thermo Fisher Scientific Human NELF Synthetic Peptide
인간 NELF 단백질의 중심부 17개 아미노산 서열을 기반으로 한 합성 펩타이드. 항체 차단용 블로킹 펩타이드로 사용 가능. 정제된 액상 형태로 제공되며 PBS 버퍼에 0.1% BSA 및 sodium azide 포함. 연구용으로만 사용.
- 카탈로그번호
- PEP1551
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific Human NELF Synthetic Peptide
Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 17 amino acids near the center of human NELF.
PEP-1551 can be used as a blocking peptide with polyclonal antibody PA5-34508.
Target Information
NELF (nasal embryonic luteinizing hormone-releasing hormone factor) is a 530 amino acid transcription factor involved in:
- Migration of LHRH neurons
- Outgrowth of olfactory axons
- Suppression of transcription elongation
NELF is expressed in the peripheral and central nervous system during embryonic development, and highly expressed in adult testis, kidney, and brain.
It couples NMDA receptor signaling to the nucleus. NELF knockdown impairs GnRH neuronal migration of NLT cells in vitro, and the gene encoding NELF has been linked to Idiopathic Hypogonadotropic Hypogonadism (IHH), a disorder resulting in impaired pubertal maturation and reproductive function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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