Thermo Fisher Scientific GSTM2 Polyclonal Antibody

Applications and Tested Dilution

• Western Blot (WB): 1:500–1:1,000

Product Specifications

Product Specific Information

The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. Purity is greater than 95% as determined by SDS-PAGE.

Target Information

Eight distinct classes of soluble cytoplasmic mammalian glutathione S-transferases (GSTs) have been identified: alpha, kappa, mu, omega, pi, sigma, theta, and zeta.
GSTM2 belongs to the mu class, which functions in the detoxification of electrophilic compounds such as carcinogens, therapeutic drugs, environmental toxins, and oxidative stress products by conjugation with glutathione.
Cytosolic and membrane-bound forms of GSTs are encoded by two distinct supergene families. The mu class genes are located on chromosome 1p13.3 and are highly polymorphic, influencing susceptibility to toxins and drug efficacy.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.