Thermo Fisher Scientific TGR5 Polyclonal Antibody
TGR5 단백질을 인식하는 Rabbit Polyclonal 항체로, 인간 시료에 반응합니다. IHC(P)에서 18 µg/mL로 검증되었습니다. 항원 친화 크로마토그래피로 정제되었으며, PBS에 0.1% sodium azide가 포함된 액상 형태입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 18 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 16 amino acid peptide from 1st cytoplasmic domain of human TGR5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551613 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Gorilla, Gibbon, Marmoset, Elephant (100%)
Monkey, Rabbit, Horse (94%)
Mouse, Bat, Bovine, Hamster (88%)
Target Information
This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. The enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces intracellular cAMP production, activation of a MAP kinase signaling pathway, and receptor internalization. The receptor is implicated in suppression of macrophage functions and regulation of energy homeostasis by bile acids. Alternative splicing results in multiple transcript variants encoding the same protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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