Thermo Fisher Scientific TGR5 Polyclonal Antibody
Human TGR5 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 9 µg/mL 농도로 검증됨. 항원 친화 크로마토그래피로 정제된 액상 형태이며, 0.87 mg/mL 농도. PBS 버퍼에 0.1% sodium azide 포함, 연구용으로만 사용 가능.
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Thermo Fisher Scientific TGR5 Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 9 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 18 amino acid peptide from 3rd cytoplasmic domain of human TGR5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.87 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551614 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Gorilla, Gibbon (100%); Monkey, Marmoset, Rabbit (94%).
Target Information
This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily.
It functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor.
The receptor is implicated in suppression of macrophage functions and regulation of energy homeostasis by bile acids.
Alternative splicing results in multiple transcript variants encoding the same protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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